Faster Steps, Shorter Stays

Across more than 12,600 knee replacements, NanoKnee patients frequently:

  • Are standing within 30 minutes after surgery
  • Return home roughly two hours following their procedure
  • Ease back into exercise and sports, many higher-impact activities included, once their surgeon approves

Before you're ever on the operating table, your CT scan becomes a 3D model that settles your implant's size, position and alignment.

Read how 3D surgical planning works →

What the Recovery Numbers Show

Figure What it measures
65 minutes Among 876 NanoKnee patients, the median interval between surgery and a first walk. Half reached that milestone faster.
96% Patients walking within two hours of surgery, with 88% doing so inside 90 minutes.
125° Median immediate knee flexion in the recovery unit across 720 patients (middle half: 120° to 134°).
Same day All NanoKnee knee replacements are outpatient, which means you'll recover at home.

In contrast, a prospective study across 19 hospitals found only 5.6% of total knee replacement patients walked on the day of surgery, with 70% walking by the end of the next day.[15] Figures shown are medians and proportions from NanoKnee post-anesthesia recovery records with data for each measure (walking: 876 patients; flexion: 720 patients). Individual results vary.

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How NanoKnee and Traditional Knee Replacement Differ, Point by Point

vs
Traditional Knee Replacement
Pre-surgical planning check mark logo Biomedical engineers build a CT-based 3D plan, then your surgeon approves it X-ray templates, often finalized while the operation is underway
Alignment philosophy check mark logo Tailored to your knee's pre-arthritic shape (restricted inverse kinematic alignment) One neutral mechanical alignment target used for everyone
Access to the knee check mark logo A muscle-sparing route, subvastus among them, for the right candidates A standard medial parapatellar incision through the quadriceps tendon
Anesthesia choice check mark logo Spinal anesthesia with sedation General anesthesia, which hospitals nationwide still use most
First walk check mark logo A median of 65 minutes post-surgery (876 patients) Just 5.6% walked on surgery day in a 19-hospital study[15]
Where you recuperate check mark logo At home, typically 1–2 hours after surgery In the hospital, often for one to three days
Therapy model check mark logo A home exercise program led by your surgeon, tracked in the NanoKnee app Weeks of scheduled outpatient therapy

Your Oklahoma City Doctor

At NanoKnee, we've brought together a team of elite surgeons renowned for their expertise and dedication to excellence in joint replacement. Our specialists, leaders in their field, leverage NanoKnee's innovative surgical techniques to provide unparalleled care. With a focus on advanced, minimally invasive procedures, our team is committed to delivering the latest treatments to help you achieve a faster recovery and improved quality of life.

Christopher Tkach, MD

Christopher Tkach, MD

Dr. Christopher K. Tkach is an Adult Reconstruction Specialist at NanoKnee®, specializing in advanced knee and hip replacement designed to restore mobility efficiently while preserving a natural fe...

Learn More about Christopher Tkach, MD

Thomas K. Tkach, MD

Thomas K. Tkach, MD

Dr. Thomas Tkach, MD, is a board-certified orthopedic surgeon with over two decades of experience helping patients live with total freedom and confidence in their joints. He specializes in hip and ...

Learn More about Thomas K. Tkach, MD

Four Ways NanoKnee Changes Knee Replacement

Four elements distinguish NanoKnee. Ask about each one when you meet with a knee surgeon.

Engineering your surgery in advance

Our biomedical engineers turn your CT scan into a 3D model and use it to determine your implant's size, position and alignment. Your surgeon reviews the finished plan and gives approval before surgery.

Learn about our 3D planning process →

Recovering at home from day one

A meta-analysis spanning 20 studies and over 580,000 cases found that outpatient knee replacement did not raise the risk of complications or readmission compared with inpatient surgery.[9] You'll head home in the Oklahoma City area the same day and recover with a home program.

Put NanoKnee side by side with other programs →

Alignment true to your knee

Your plan restores the joint line and alignment your knee had before arthritis instead of applying a standard neutral target to every patient. With your ligaments working as they naturally should, your knee feels balanced and like your own.

A quadriceps-sparing option

Randomized trials have shown that quadriceps-sparing approaches offer early benefits such as decreased pain and faster recovery.[8] NanoKnee surgeons offer these approaches to appropriate candidates, including the subvastus, or “Southern,” approach.

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Tackling the Leading Causes of Knee Replacement Trouble

When a knee replacement fails early, the implant is usually not the culprit. A review of revision surgeries at six U.S. joint replacement centers pointed to loosening, instability, infection, stiffness and malalignment as the leading causes, with the authors concluding that early failures are mainly surgeon-dependent.[1]

Component position matters well into the future, too. Among 6,070 knee replacements, poorly positioned components were associated with higher failure rates.[2] Even without a failure, about one out of every five patients is dissatisfied with the result.[3] That's why your NanoKnee plan receives as much care as your operation.

We model your case in 3D from your CT scan, sizing and aligning the implant to your anatomy and mapping ligament balance through your range of motion, all before surgery begins. A properly balanced, accurately positioned knee helps patients get moving fast and stay moving.

A Knee Shaped Like Your Own

Every knee is different, so NanoKnee's 3D plan doesn't force yours toward a universal neutral target. It restores your joint surfaces and alignment to their pre-arthritis shape, with the goal of a strong, flexible knee that feels natural from day one.

man running

Your Day of Surgery

NanoKnee knee replacement is an outpatient operation. Spinal anesthesia and sedation keep you comfortable and unaware, so a general anesthetic isn't necessary. Expect the surgery to last about 90 minutes.

Your care team will help you stand about 30 minutes after the procedure, and most patients are headed home within two hours. Your new knee is ready to bend and bear weight immediately.

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Recovery Milestones

Your rehab happens mostly at home, through an exercise program your surgeon designs, rather than at a therapy clinic. Here's what most NanoKnee patients experience:

  1. Days 7–14: everyday confidence. Most patients handle routine tasks on their own, from preparing a simple meal to short trips out of the house.
  2. Weeks 2–4: more strength, more stamina. Your program progresses, and moderate activities such as longer walks and stationary biking become part of your week.
  3. Weeks 4–8: active again. Most patients are back to the active life they hoped surgery would restore, moving forward at their surgeon's recommended pace.

About 85% of knee replacement patients return to moderate-impact physical activity at a median of roughly four months, according to published research.[4] Your surgeon will personalize the pace of your recovery.

Staying Active With Your New Knee

Movement is good medicine for a new knee. To support your recovery and long-term joint health, consider:

  • Walking
  • Biking
  • Water aerobics
  • Tai chi
  • Yoga
  • Tennis
  • Strengthening exercises

When healing is complete, there's every reason to get back out there: most patients resume the sports and activities they enjoy without restrictions.

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Knee Replacement Frequently Asked Questions

How long will my new knee keep working?

Potentially for decades. The biggest analysis of national joint registries to date found that a quarter century after surgery, about 82% of total knee replacements and 70% of partial knee replacements were still in place.[5] Getting the implant's position right is a key part of reaching that kind of lifespan.

How does precise positioning affect implant life?

It's one of the few factors a surgical team can directly control. Component position and balance both influence how long a knee replacement lasts,[2] so NanoKnee pairs advanced 3D modeling and engineering with FDA-cleared implants to plan exactly where your implant should sit and how it should be aligned for your anatomy.

What kind of patient is NanoKnee meant for?

NanoKnee is meant for people who need a knee replacement and would like to recover at home, keep living actively, and have an implant planned for their specific anatomy. It was developed for active patients looking for the best possible function afterward, including younger adults and healthy older adults. Your surgeon will review your imaging, health, history and goals at your consultation to see whether you're a candidate.

How risky is knee replacement surgery?

Serious complications are uncommon. Knee replacement ranks among the most widely performed and heavily studied operations in the country, with more than 4.4 million hip and knee replacements recorded in the American Joint Replacement Registry since 2012.[6] Some risks also depend on choices made before surgery even starts. Anesthesia is one example. In a national analysis of more than 380,000 joint replacements, spinal (neuraxial) anesthesia was associated with lower 30-day mortality and fewer in-hospital complications than general anesthesia.[7] Board-certified orthopedic surgeons perform NanoKnee procedures with spinal anesthesia and sedation.

Why doesn't NanoKnee use standard alignment?

Because not every healthy knee is built to the standard. A substantial share of adults naturally have knees that aren't in “neutral” mechanical alignment.[10] NanoKnee instead uses restricted inverse kinematic alignment (iKA), a personalized approach that restores your natural tibial joint line and alignment within safe limits. In a matched series, iKA patients reported greater satisfaction and higher Oxford Knee Scores at one year than patients aligned to an adjusted mechanical target.[11] Your plan is based on your CT scan and reviewed by your surgeon before surgery.

Is partial knee replacement an option for me?

It could be, if arthritis has damaged only part of your knee. NanoKnee surgeons perform partial (unicompartmental) and bicompartmental knee replacement, which resurface just the affected one-third or two-thirds of the joint and preserve your ligaments and healthy bone. In a randomized trial of 528 patients with arthritis confined to the inner compartment, partial knee replacement produced equivalent improvement with fewer complications.[12][13] Your NanoKnee surgeon will discuss which approach matches your anatomy and knee condition.

What's the gentlest way to replace a knee?

If your arthritis is limited to one compartment, a Nano partial knee replacement is the least invasive, since it removes the least bone and keeps your ligaments intact.[12] When a total knee replacement is needed, planning and surgical approach make more difference than incision length. Thanks to advanced 3D modeling, NanoKnee surgeons can use a quadriceps-sparing approach for suitable candidates, reaching the joint without cutting the quadriceps tendon. Randomized trials show this lowers pain in the first days after surgery.[8]

Do I have to be fully put under for knee replacement?

No. NanoKnee surgeons rely on spinal (regional) anesthesia, a local anesthetic block and “twilight” sedation, which together keep you comfortable and unaware during the procedure without general anesthesia. A national analysis of more than 380,000 joint replacements linked spinal anesthesia to lower 30-day mortality and fewer complications than general anesthesia.[7] Your team will use general anesthesia only if it's the safer choice in your case.

How long after surgery can I go home?

Usually about two hours. NanoKnee knee replacement is an outpatient procedure, and in a meta-analysis of 20 studies, appropriately selected outpatients had complication and readmission rates comparable to inpatients.[9] Your surgeon will confirm ahead of time that a same-day return home is appropriate for you.

How much time will my surgery take?

Plan on roughly 90 minutes. Your implant's size, position and alignment are decided during planning, so fewer judgments have to be made under time pressure once surgery is underway.

What does the recovery timeline look like?

Most NanoKnee patients are walking within 90 minutes of surgery and doing light activities during the first week. A rough guide:

  • 7–14 days: routine daily life
  • 2–4 weeks: moderate exertion
  • 4–8 weeks: an active lifestyle once more
Your surgeon will set the pace based on how you're healing.

Will I recover at home or in a therapy clinic?

Most NanoKnee patients recover at home. Instead of formal outpatient physical therapy, you'll follow a surgeon-guided exercise program that starts with walking, isometrics and stretching right away and advances to strengthening, biking, and activities like golf and hiking. The NanoKnee app helps you track progress and stay in contact with your care team.

Will I be able to play pickleball, golf or tennis again?

Most NanoKnee patients get back to the activities they enjoy, whether that's tennis, golf, hiking, cycling, running or skiing.

Will my knee bend normally after surgery?

Most NanoKnee patients regain the bend they need for daily life and sport, and many recover motion that arthritis had slowly taken away. Your 3D plan is built to balance your ligaments across the full range of motion, supporting a knee that fully bends and straightens. In our recovery-unit records, 720 NanoKnee patients had a median knee flexion of 125° right after surgery, with half falling between 120° and 134°.

When will my incision be fully healed?

Generally within two weeks, although you should continue protecting the area for the first two to three months. NanoKnee procedures use a cosmetic, plastic-surgical closure to help keep scarring minimal.

What risks does knee replacement carry?

Possible risks include infection, blood clots, stiffness, instability, implant loosening over time, and complications related to anesthesia. NanoKnee's surgical processes and proprietary 3D Blueprinting® target specific risks: spinal anesthesia is associated with fewer perioperative complications than general anesthesia,[7] and pre-operative 3D planning focuses on the position and balance problems that rank among the leading causes of early revision.[1] Your NanoKnee surgeon will go over the risks that apply to your situation.

What might I notice in the months after surgery?

Most patients notice function returning and arthritis pain fading as the months go by. Some numbness around the incision and an occasional click are common and typically harmless. Your surgeon will keep track of your recovery and step in if anything isn't progressing as it should.

How is NanoKnee billed to insurance?

NanoKnee surgery is billed as a knee replacement, which Medicare and most commercial health plans cover when it's medically necessary. The pre-operative 3D planning and engineering aren't covered by insurance, so depending on your plan, you may be responsible for up to $8,500 of that cost. Our patient navigators will confirm what you'll owe before you commit to surgery, and financing is available for non-covered amounts.

Can older adults choose NanoKnee?

Yes. Knee replacement is a common procedure for older adults with advanced arthritis, and it can bring big improvements in mobility and quality of life. Candidacy hinges on your general health, not your birth year, and every NanoKnee patient is evaluated before surgery. NanoKnee's standard spinal anesthesia is associated with fewer perioperative complications than general anesthesia.[7]

Where does AI fit into NanoKnee, and is a robot involved?

AI fits in only at the planning stage, where it helps our biomedical engineers build a 3D model from your CT scan; your surgeon then reviews and approves the plan. No robot is used in the operating room, and your surgeon performs the procedure. NanoKnee's precision is built during planning, not supplied by operating room technology.

Sources

  1. Schroer WC, Berend KR, Lombardi AV, Barnes CL, Bolognesi MP, Berend ME, Ritter MA, Nunley RM. Why are total knees failing today? Etiology of total knee revision in 2010 and 2011. J Arthroplasty. 2013;28(8 Suppl):116-119. doi:10.1016/j.arth.2013.04.056
  2. Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME, Malinzak RA. The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am. 2011;93(17):1588-1596. doi:10.2106/JBJS.J.00772
  3. Bourne RB, Chesworth BM, Davis AM, Mahomed NN, Charron KDJ. Patient satisfaction after total knee arthroplasty: who is satisfied and who is not? Clin Orthop Relat Res. 2010;468(1):57-63.
  4. Braz R, Gomes E, Valente C, Ahmed H, Moursy M, Delgado D, Sanchez M, Andrade R, Espregueira-Mendes J. High rate of return to low-impact physical activity or sports after total and unicompartmental knee arthroplasty: a systematic review with meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2026. doi:10.1002/ksa.70267
  5. Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet. 2019;393(10172):655-663. doi:10.1016/S0140-6736(18)32531-5
  6. American Academy of Orthopaedic Surgeons. American Joint Replacement Registry (AJRR): 2025 Annual Report. Rosemont, IL: AAOS; 2025.
  7. Memtsoudis SG, Sun X, Chiu YL, Stundner O, Liu SS, Banerjee S, Mazumdar M, Sharrock NE. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology. 2013;118(5):1046-1058. doi:10.1097/ALN.0b013e318286061d
  8. Berstock JR, Murray JR, Whitehouse MR, Blom AW, Beswick AD. Medial subvastus versus the medial parapatellar approach for total knee replacement: a systematic review and meta-analysis of randomized controlled trials. EFORT Open Rev. 2018;3(3):78-84. doi:10.1302/2058-5241.3.170030
  9. Gong S, Yi Y, Wang R, Han L, Gong T, Wang Y, Shao W, Feng Y, Xu W. Outpatient total knee and hip arthroplasty present comparable and even better clinical outcomes than inpatient operation. Front Surg. 2022;9:833275. doi:10.3389/fsurg.2022.833275
  10. Bellemans J, Colyn W, Vandenneucker H, Victor J. The Chitranjan Ranawat Award: is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res. 2012;470(1):45-53.
  11. Winnock de Grave P, Luyckx T, Claeys K, Tampere T, Kellens J, Müller J, Gunst P. Higher satisfaction after total knee arthroplasty using restricted inverse kinematic alignment compared to adjusted mechanical alignment. Knee Surg Sports Traumatol Arthrosc. 2022;30(2):488-499. doi:10.1007/s00167-020-06165-4
  12. Beard DJ, Davies LJ, Cook JA, MacLennan G, Price A, Kent S, Hudson J, Carr A, Leal J, Campbell H, Fitzpatrick R, Arden N, Murray D, Campbell MK; TOPKAT Study Group. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet. 2019;394(10200):746-756. doi:10.1016/S0140-6736(19)31281-4
  13. Beard DJ, Davies LJ, Cook JA, MacLennan G, Hudson J, Price AJ, Carr AJ, Little M, Leal J, Fitzpatrick R, Murray DW, Campbell MK; TOPKAT Study Group. Assessing clinical and cost effectiveness of total versus partial knee replacement (TOPKAT): 10-year follow-up of a multicentre, randomised controlled trial. Lancet Rheumatol. 2026;8(2):e116-e126. doi:10.1016/S2665-9913(25)00250-4
  14. Witjes S, Gouttebarge V, Kuijer PPFM, van Geenen RCI, Poolman RW, Kerkhoffs GMMJ. Return to sports and physical activity after total and unicondylar knee arthroplasty: a systematic review and meta-analysis. Sports Med. 2016;46(2):269-292. doi:10.1007/s40279-015-0421-9
  15. Chua MJ, Hart AJ, Mittal R, Harris IA, Xuan W, Naylor JM. Early mobilisation after total hip or knee arthroplasty: a multicentre prospective observational study. PLoS One. 2017;12(6):e0179820. doi:10.1371/journal.pone.0179820
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