Walk Sooner, Heal at Home

Backed by a proven record of over 12,600 knee replacements, NanoKnee surgeons deliver results that get you back on your feet quickly and safely. Our patients routinely:

  • Stand and bear weight within 30 minutes of surgery.
  • Return to the comfort of home roughly two hours post-procedure.
  • Safely resume their favorite sports and workouts, including higher-impact activities—once cleared by their surgeon.

Your recovery begins with proactive planning. Long before your procedure, our biomedical engineers transform your CT scan into a precise 3D model, establishing your implant’s exact size, positioning, and alignment before you ever enter the operating room.

Explore the science of 3D surgical planning →

NanoKnee Recovery Benchmarks

Figure What it measures
65 minutes How long it took the median NanoKnee patient to walk after surgery (876 patients). Half walked before reaching that mark.
96% Patients who were walking by the two-hour mark after surgery; 88% were walking by 90 minutes.
125° The median knee flexion our recovery unit recorded across 720 patients; the middle half measured from 120° to 134°.
Same day No overnight stay: NanoKnee knee replacements are performed only as outpatient procedures.

For perspective, a prospective multi-center study across 19 hospitals found that only 5.6% of conventional total knee replacement patients walked on the day of surgery, with 70% walking by the end of postoperative day one. In comparison, NanoKnee metrics reflect medians and proportions gathered directly from post-anesthesia recovery unit (PACU) records tracking these specific recovery milestones (walking: 876 patients; flexion: 720 patients). As with any surgical procedure, individual patient results and timelines vary.

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Side by Side: NanoKnee and Traditional Knee Replacement

vs
Traditional Knee Replacement
Pre-op preparation check mark logo A 3D plan from your CT scan, designed by biomedical engineers and approved by your surgeon Templating on X-rays, typically finished during the operation
Knee alignment check mark logo Personalized to the way your knee was shaped before arthritis (restricted inverse kinematic alignment) A uniform neutral mechanical alignment for all knees
Surgical technique check mark logo Muscle-sparing, including the subvastus approach, when appropriate The standard medial parapatellar approach, which cuts through the quadriceps tendon
Anesthetic plan check mark logo Spinal anesthesia alongside sedation General anesthesia, still the national norm
Time to first walk check mark logo A median of 65 minutes (876 patients) A 19-hospital study found only 5.6% walked the same day[15]
Where recovery happens check mark logo Home, usually within one to two hours of surgery A hospital admission of one to three days is still typical
Rehabilitation check mark logo Surgeon-directed exercises at home, tracked in the NanoKnee app Outpatient physical therapy lasting several weeks

Your Layton Doctors

At NanoKnee, our hand-selected surgeons are proven leaders in joint replacement, chosen for exceptional surgical craftsmanship and a steadfast dedication to patient care. By pairing their elite expertise with NanoKnee’s innovative, minimally invasive techniques, we deliver outstanding clinical results. Our advanced approaches accelerate your recovery, ensure lasting joint stability, and empower you to return to the active life you love.

Daniel Sumko, DO

Daniel Sumko, DO

Dr. Sumko is a board-certified orthopedic surgeon whose practice centers on adult reconstruction, including hip and knee replacement. After completing fellowship training at The CORE Institute in P...

Learn More about Daniel Sumko, DO

Why NanoKnee Isn't a Typical Knee Replacement

NanoKnee differs in four specific ways. Use them as a checklist when you talk with any knee surgeon.

A Personalized Plan Engineered Before Surgery

Long before you enter the operating suite, our biomedical engineers transform your CT scan into a precise 3D model of your knee. Using this digital map, they determine the exact sizing, placement, and alignment for your implant. Your surgeon then meticulously reviews and approves every detail of the plan well ahead of your procedure.

See how our engineers plan your surgery →

Same-Day Discharge with Spinal Anesthesia

Clinical evidence confirms you can safely recover outside of a traditional hospital setting. A comprehensive meta-analysis of 20 studies spanning over 580,000 cases showed that outpatient knee replacement carries no higher risk of complications or hospital readmission than inpatient care. Under gentle spinal anesthesia, you will head straight home to Layton the very day of your procedure to continue your recovery with a structured home rehabilitation program.

Compare NanoKnee with other knee replacement options →

Alignment Tailored to Your Natural Knee

Your new knee is aligned to restore the natural joint line you were born with before arthritis altered your anatomy, rather than a generic, one-size-fits-all neutral angle. By preserving your body's native alignment, your ligaments continue to function just as they always have, delivering a joint that feels remarkably stable, balanced, and natural.

Preserving Your Quadriceps for a Smoother Recovery

Clinical trials demonstrate that quadriceps-sparing techniques offer distinct early advantages, including significantly reduced post-operative pain and accelerated healing. For appropriate candidates, NanoKnee surgeons prioritize these muscle-preserving methods, including the subvastus approach, often referred to as the “Southern” technique, to protect vital muscle tissue and help you regain strength faster.

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Reducing the Risk of Common Knee Replacement Setbacks

The implant hardware itself is rarely why a knee replacement fails prematurely. In a landmark study analyzing revision surgeries across six major U.S. joint replacement centers, researchers found that the leading causes of early failure were loosening, instability, infection, stiffness, and malalignment, concluding that early outcomes hinge largely on surgical precision and technique. That is why NanoKnee pairs advanced digital pre-planning with elite, specialized surgeons to ensure accurate placement from day one.

Accurate placement remains critical for years to come. In an extensive clinical series of 6,070 knee replacements, poorly positioned components were directly linked to elevated failure rates. Even when an implant does not technically fail, approximately one in five patients still reports lingering dissatisfaction with their results. That is why NanoKnee devotes just as much meticulous planning before surgery as to the procedure itself, ensuring your joint feels balanced and performs reliably for the long haul.

Using your CT scan, we construct a precise 3D digital model of your joint well before surgery begins. This allows our team to customize the sizing and alignment of your implant directly to your natural anatomy, while mapping out ligament balance across your entire range of motion before the first incision is ever made. A joint that is accurately positioned and dynamically balanced gives you the confidence to get on your feet quickly and maintain an active lifestyle for years to come.

Alignment Designed Around Your Pre-Arthritis Knee

NanoKnee’s 3D planning moves beyond standardized, one-size-fits-all targets. Instead of forcing every joint into a generic neutral alignment, we replicate the precise contours and joint angles you had before arthritis developed. By restoring your native anatomy, we deliver a stable, flexible knee that moves naturally and feels familiar from your very first steps.

A man running

Inside Your Procedure Day

Your knee replacement is performed as an outpatient procedure under gentle spinal anesthesia with light sedation. You remain completely comfortable and relaxed throughout surgery without the lingering side effects or grogginess of general anesthesia.

Most procedures take about 90 minutes. Roughly half an hour after surgery, our clinical team will assist you to your feet to take your first steps. Most patients are on their way home in about two hours with a new knee ready to bend and support full weight right away.

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Recovery, Stage by Stage

Rather than demanding weeks of exhausting travel to outpatient clinics, NanoKnee empowers most patients to recover comfortably through a surgeon-designed home rehabilitation program. Recovery typically progresses along this timeline:

  • Days 7–14 (Independence at Home): Confidently navigate your home, handle personal care, and manage daily household routines.
  • Weeks 2–4 (Building Strength & Endurance): Progress to more challenging exercises, longer neighborhood walks, and low-impact cross-training like stationary cycling.
  • Weeks 4–8 (Back in Action): Resume the active lifestyle and hobbies that brought you to surgery, progressing safely under your surgeon's personalized guidance.

Clinical research shows that roughly 85% of knee replacement patients return to moderate-impact physical activities within a median of four months. Because every recovery is unique, your NanoKnee surgeon will monitor and tailor your milestones at every step.

Protecting Your Knee Over Time

Consistent, low-impact movement is essential for building joint stability and maintaining long-term knee health. Ideal activities to keep you moving include:

  • Walking and hiking
  • Cycling (road or stationary)
  • Water aerobics and swimming
  • Tai chi and yoga
  • Tennis and pickleball
  • Targeted strength training

Once fully healed, you won’t have to sideline the sports and pastimes you love most. Patients return to an active, fulfilling lifestyle without restrictions.

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Knee Replacement Frequently Asked Questions

Can a knee replacement last 25 years?

Many do. In the largest analysis of national joint registry data, roughly 82% of total knee replacements and 70% of partial knee replacements were still functioning a quarter century after surgery.[5] Precise positioning is one of the factors that helps a knee replacement reach that milestone.

How does NanoKnee's planning support long-term results?

NanoKnee targets the details that shape how long an implant performs. We combine precise 3D modeling and biomedical engineering with FDA-cleared implants to build a plan that positions and aligns your implant to match your anatomy. Component position and balance are among the factors within a surgical team's control that affect the lifespan of a knee replacement.[2]

Who does NanoKnee work best for?

NanoKnee is designed for people who need a knee replacement and want to recover at home, stay active, and have their implant planned for their own anatomy. It serves active patients seeking excellent function after surgery, from younger adults to older patients in good general health. Whether you're a candidate depends on your imaging, health, history and goals, all of which your surgeon evaluates at your consultation.

What makes knee replacement a safe choice today?

Decades of research and millions of procedures stand behind it. Knee replacement is one of the most commonly performed and most studied operations in the U.S., and the American Joint Replacement Registry has documented more than 4.4 million hip and knee replacements since 2012. [6] Serious complications are infrequent, and certain risks can be lowered through decisions made before surgery. For example, a national analysis of more than 380,000 joint replacements found that spinal (neuraxial) anesthesia was associated with lower 30-day mortality and fewer in-hospital complications than general anesthesia.[7] NanoKnee procedures are performed with spinal anesthesia and sedation by board-certified orthopedic surgeons.

What is restricted inverse kinematic alignment?

Restricted inverse kinematic alignment (iKA) is the personalized method NanoKnee uses to restore your natural tibial joint line and alignment, staying within safe limits. Healthy knees vary, and a substantial share of adults naturally have knees that don't sit in “neutral” mechanical alignment. [10] In a matched series, patients aligned with iKA reported higher satisfaction and better Oxford Knee Scores at one year than patients aligned to an adjusted mechanical target.[11] Your iKA plan is built from your CT scan before surgery and reviewed by your surgeon.

Do I need a total knee replacement, or will a partial work?

That depends on how much of your knee is affected. When arthritis is limited to one or two areas, NanoKnee surgeons can perform a partial (unicompartmental) or bicompartmental knee replacement, resurfacing only the damaged one-third or two-thirds of the joint and preserving your ligaments and healthy bone. A randomized trial of 528 patients with arthritis in the inner compartment showed partial knee replacement delivered equivalent improvement with fewer complications.[12][13] Your NanoKnee surgeon will help you weigh the options based on your anatomy and knee condition.

How does NanoKnee minimize surgical trauma?

If arthritis affects just one compartment, a Nano partial knee replacement is the least invasive choice, removing the smallest amount of bone and keeping your ligaments in place.[12] For total knee replacement, planning and approach have a bigger effect than incision length. With our advanced 3D modeling, NanoKnee surgeons can use a quadriceps-sparing approach for appropriate candidates, reaching the joint without cutting the quadriceps tendon. Randomized trials show this approach reduces pain during the first days of recovery.[8]

How will I be kept comfortable during surgery?

Your NanoKnee surgeon uses spinal (regional) anesthesia with a local anesthetic block and “twilight” sedation, so you're comfortable and unaware of the procedure without a general anesthetic. In a national analysis of more than 380,000 joint replacements, spinal anesthesia was associated with lower 30-day mortality and fewer complications than general anesthesia.[7] A general anesthetic remains an option for the rare patients for whom it's safer.

Will I spend the night after my knee replacement?

Most patients don't. Because NanoKnee is an outpatient procedure, you'll typically be on your way home from the surgery center within about two hours. A meta-analysis of 20 studies found that appropriately chosen outpatients had complication and readmission rates comparable to inpatients. [9] Before surgery, your surgeon will make sure going home that day suits your health and circumstances.

What's the typical length of a NanoKnee surgery?

About 90 minutes. Because your implant's size, position and alignment are already determined in your 3D plan, your surgeon doesn't have to make those choices under time pressure in the operating room.

How soon can I resume normal activities after knee replacement?

Most NanoKnee patients walk within 90 minutes of surgery and take on light activities during the first week. A general guide:

  • 7–14 days: ordinary daily activities
  • 2–4 weeks: activities of moderate intensity
  • 4–8 weeks: an active lifestyle
Recovery is different for everyone, and your surgeon will set the pace that suits you.

Is outpatient physical therapy required after NanoKnee?

Usually not. Most NanoKnee patients recover through a surgeon-guided home exercise program. You'll begin walking, isometrics and stretching right away, then move on to strengthening, biking, and activities such as golf and hiking. The NanoKnee app lets you track your progress and keep in touch with your care team.

Can I stay athletic after a knee replacement?

Most NanoKnee patients go on to enjoy activities such as hiking, cycling, golf, tennis, running and skiing.

How much flexion can I expect after surgery?

Most NanoKnee patients regain the knee flexion they need for daily activities and sports, and many get back motion they had lost to arthritis over time. Your 3D plan balances your ligaments through the full range of motion, helping your knee bend and straighten completely. Across 720 NanoKnee patients in our recovery-unit records, median flexion immediately after surgery was 125°, with the middle half of patients between 120° and 134°.

How long is the healing time for the incision?

Your incision should heal in about two weeks, but you'll protect the area for the first two to three months. Each NanoKnee procedure finishes with a cosmetic, plastic-surgical closure designed to reduce scarring.

Are there risks I should be aware of?

As with any knee replacement, possible risks include infection, blood clots, stiffness, instability, implant loosening over time, and the risks of anesthesia. NanoKnee's surgical processes and proprietary 3D Blueprinting® are designed to address specific risks: spinal anesthesia is associated with fewer perioperative complications than general anesthesia, [7] and pre-operative 3D planning targets the position and balance problems that are among the leading causes of early revision.[1] Your NanoKnee surgeon will discuss the risks relevant to you.

What should I expect long after surgery?

Over the months following surgery, most patients see their function steadily return and their arthritis pain resolve. Mild numbness near the incision and an occasional clicking sound are common and generally not a concern. Your surgeon will monitor your progress and address anything that doesn't improve as expected.

Will I have out-of-pocket costs for NanoKnee?

Possibly. Medicare and most commercial health plans cover knee replacement when it's medically necessary, and NanoKnee surgery is billed as a knee replacement. However, insurance doesn't cover the pre-operative 3D planning and engineering, and depending on your plan, you could pay up to $8,500 for that portion. Our patient navigators will confirm your coverage and expected costs before you commit to surgery, and financing is available for non-covered expenses.

Is NanoKnee appropriate for older patients?

Yes. For many people in their later years, a new knee is what restores the ability to walk, travel and stay independent. Rather than setting an age cutoff, NanoKnee surgeons look at your general health, and each patient is fully evaluated before surgery is scheduled. Spinal anesthesia, which NanoKnee uses as standard practice, is associated with fewer perioperative complications than general anesthesia.[7]

How does NanoKnee use technology without a robot?

NanoKnee's technology is used before surgery, not during it. AI helps our biomedical engineers build a 3D model from your CT scan, your surgeon reviews and approves the resulting plan, and then your surgeon performs the operation with no robot in the room. The precision comes from that detailed pre-operative planning.

Sources

  1. Schroer WC, Berend KR, Lombardi AV, Barnes CL, Bolognesi MP, Berend ME, Ritter MA, Nunley RM. Why are total knees failing today? Etiology of total knee revision in 2010 and 2011. J Arthroplasty. 2013;28(8 Suppl):116-119. doi:10.1016/j.arth.2013.04.056
  2. Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME, Malinzak RA. The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am. 2011;93(17):1588-1596. doi:10.2106/JBJS.J.00772
  3. Bourne RB, Chesworth BM, Davis AM, Mahomed NN, Charron KDJ. Patient satisfaction after total knee arthroplasty: who is satisfied and who is not? Clin Orthop Relat Res. 2010;468(1):57-63.
  4. Braz R, Gomes E, Valente C, Ahmed H, Moursy M, Delgado D, Sanchez M, Andrade R, Espregueira-Mendes J. High rate of return to low-impact physical activity or sports after total and unicompartmental knee arthroplasty: a systematic review with meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2026. doi:10.1002/ksa.70267
  5. Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet. 2019;393(10172):655-663. doi:10.1016/S0140-6736(18)32531-5
  6. American Academy of Orthopaedic Surgeons. American Joint Replacement Registry (AJRR): 2025 Annual Report. Rosemont, IL: AAOS; 2025.
  7. Memtsoudis SG, Sun X, Chiu YL, Stundner O, Liu SS, Banerjee S, Mazumdar M, Sharrock NE. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology. 2013;118(5):1046-1058. doi:10.1097/ALN.0b013e318286061d
  8. Berstock JR, Murray JR, Whitehouse MR, Blom AW, Beswick AD. Medial subvastus versus the medial parapatellar approach for total knee replacement: a systematic review and meta-analysis of randomized controlled trials. EFORT Open Rev. 2018;3(3):78-84. doi:10.1302/2058-5241.3.170030
  9. Gong S, Yi Y, Wang R, Han L, Gong T, Wang Y, Shao W, Feng Y, Xu W. Outpatient total knee and hip arthroplasty present comparable and even better clinical outcomes than inpatient operation. Front Surg. 2022;9:833275. doi:10.3389/fsurg.2022.833275
  10. Bellemans J, Colyn W, Vandenneucker H, Victor J. The Chitranjan Ranawat Award: is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res. 2012;470(1):45-53.
  11. Winnock de Grave P, Luyckx T, Claeys K, Tampere T, Kellens J, Müller J, Gunst P. Higher satisfaction after total knee arthroplasty using restricted inverse kinematic alignment compared to adjusted mechanical alignment. Knee Surg Sports Traumatol Arthrosc. 2022;30(2):488-499. doi:10.1007/s00167-020-06165-4
  12. Beard DJ, Davies LJ, Cook JA, MacLennan G, Price A, Kent S, Hudson J, Carr A, Leal J, Campbell H, Fitzpatrick R, Arden N, Murray D, Campbell MK; TOPKAT Study Group. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet. 2019;394(10200):746-756. doi:10.1016/S0140-6736(19)31281-4
  13. Beard DJ, Davies LJ, Cook JA, MacLennan G, Hudson J, Price AJ, Carr AJ, Little M, Leal J, Fitzpatrick R, Murray DW, Campbell MK; TOPKAT Study Group. Assessing clinical and cost effectiveness of total versus partial knee replacement (TOPKAT): 10-year follow-up of a multicentre, randomised controlled trial. Lancet Rheumatol. 2026;8(2):e116-e126. doi:10.1016/S2665-9913(25)00250-4
  14. Witjes S, Gouttebarge V, Kuijer PPFM, van Geenen RCI, Poolman RW, Kerkhoffs GMMJ. Return to sports and physical activity after total and unicondylar knee arthroplasty: a systematic review and meta-analysis. Sports Med. 2016;46(2):269-292. doi:10.1007/s40279-015-0421-9
  15. Chua MJ, Hart AJ, Mittal R, Harris IA, Xuan W, Naylor JM. Early mobilisation after total hip or knee arthroplasty: a multicentre prospective observational study. PLoS One. 2017;12(6):e0179820. doi:10.1371/journal.pone.0179820
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